| Article | Drug/Class | Study design | Sample size | Follow-up (months) | Withdrawal schedule |
| Coll 2000 | Levothyroxine | Before-and-after study | 22 | 3 | Dose reduced by as close to one-half as was practically possible (125 mcg daily reduced to 75 mcg daily; 75 mcg daily reduced to 50 mcg daily) |