Article | Drug/Class | Study design | Sample size | Follow-up (months) | Withdrawal schedule |
Dawson 1999 | Cilostazol, pentoxifylline | RCT continuation study | 60 | 7.5 | Abrupt discontinuation/replacement with placebo |
Derogar 2013 | Aspirin | Retrospective cohort study | 118 | Median 24 | Not described |
Gonzalez-Perez 2017 | Aspirin | Retrospective cohort study | 547 | 60 | Not described |
Piccolo 2017 | Dual antiplatelet therapy: aspirin + clopidogrel | RCT | 1970 | 24 | Abrupt discontinuation |
Sambu 2011 | Clopidogrel | Before-and-after study | 38 | 1 | Not described |
Yedidya 2012 | Clopidogrel | RCT | 20 | 24 | Tapering group: tapering regimen over four weeks with clopidogrel 75 mg every other day Abrupt cessation group: abrupt discontinuation |