| Article | Drug/Class | Study design | Sample size | Follow-up (months) | Withdrawal schedule |
| Avraham 2018 | PPI | Before-and-after study | 10 | 3 | Halving the dose; initiating famotidine if required |
| Lee 2017 | PPI | Before-and-after study | 28 | 2 | Abrupt discontinuation |
| McDonald 2015 | PPI | Before-and-after study | 209 | Until hospital discharge | At treating physician’s discretion (eg, could be modified, weaned, abruptly discontinued) |
| McIntyre 2017 | Quinine, diuretics, alpha-1 blockers, PPI, statins | Before-and-after study | 240 | 6 | Not described |
| Pratt 2017 | PPI | Interrupted time series | Cohort 1 62,460 Cohort 2 67,565 | 120 | Not described |
| Reeve 2015 | PPI | Before-and-after study | 6 | 6 | Halving the dose every 2 weeks and reducing to as-needed if the participant remained symptom-free on low-dose |
| Wahking 2018 | PPI | Retrospective cohort study | 537 | 3 | Abrupt discontinuation or dose reduction |